Some Definitions

eth-i-cal: (adj.) 1. Relating to morals, especially as concerning human conduct. 2. Morally correct.

le-gal: (adj.) 1. Of or based on law. 2. Appointed or required by law. 3. Permitted by law.

so-cial: (adj.) 1. Of or relating to society and its organization. 2. Concerned with the mutual relations of human beings. 3. Living in organized communities.

pol-i-cy: (n.) 1. Course or principle of action adopted or proposed by a government, party, business or individual, etc.

Definitions adapted from the Oxford Desk Dictionary and Thesaurus.

 

Stem Cell Research: Beyond Hype, Real Hope

The three broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, adult stem cells, which are found in adult tissues, and cord blood stem cells, which are found in the umbilical cord.

In a developing embryo, stem cells are able to differentiate into all of the specialized embryonic tissues.

In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells.

As stem cells can be readily grown and transformed into specialised cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed.

In particular, embryonic cell lines, autologous embryonic stem cells generated through therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates.

Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues.

Also known as somatic stem cells, they can be found in children, as well as adults. A great deal of adult stem cell research has focused on clarifying their capacity to divide or self-renew indefinitely and their differentiation potential.

Bio Science Companies


BD Biosciences

BD Biosciences, a segment of BD, is one of the world’s leading businesses focused on bringing innovative research and clinical tools to life scientists and clinicians. Its product lines include: flow cytometers; cell imaging systems; monoclonal antibodies; research reagents; diagnostics assays; and tools to help grow tissue and cells.

Invitrogen

Invitrogen Corporation provides products and services that support academic and government research institutions and pharmaceutical and biotech companies worldwide in their efforts to improve the human condition. The company provides essential life science technologies for disease research, drug discovery, and commercial bioproduction. Invitrogen's R&D efforts are focused on breakthrough innovation in biological discovery including stem cell science – its products are referenced in a 100% of the most cited stem cell research papers. For more information, visit www.invitrogen.com/stemcell

Millipore

Global scientific advancements in biomedical and academic research laboratories are aided by Millipore’s innovative biological reagents. Millipore improves productivity by offering kits, tools, reagents and cell lines for applications such as stem cell, cell signaling and diagnostics research. Millipore is a leading provider of mouse embryonic stem cells and reagents as well as human adult and primary cells that are used to foster growth and discovery for disease treatment and development.


Exhibitors

Amaxa

Amaxa develops and commercializes innovative products for the transfer of DNA or siRNA into cells. Its unique Nucleofector® technology provides a breakthrough tool for the highly efficient, non-viral transfection of primary cells and hard-to-transfect cell lines, enabling researchers to now use primary cells in their gene transfer experiments in basic research and drug development. The recently introduced Nucleofector® 96-well-Shuttle® System now also allows high throughput transfection in 96-well format.



BioE

BioE is a biomedical company providing human cord blood stem cells as enabling, high-quality cellular tools for drug discovery and therapeutic research. The company’s novel Multi-Lineage Progenitor Cell™ (MLPC™) is a genetically normal, multi-potent, clonal cell derived from human umbilical cord blood and obtained using PrepaCyte®, the company’s proprietary cell isolation platform. The MLPC™ provides clinicians and researchers a flexible, long-term and non-controversial tool for therapeutic research, drug discovery, and screening.

BioSpherix

ULTIMATE STEM CELL WORKSTATION, an advanced new incubation system. Multiple independent high performance O2/CO2/NO/CO incubators offer unprecedented new ability to manipulate stem cell phenotype. Integrated inside matching aseptic O2/CO2/NO/CO controlled-atmosphere isolators along with microscopes, sorters, centrifuges, etc., this unique system provides the first economical and practical alternative to cleanrooms for GMP-compliant production of stem cells for therapy.

Cell Signaling Technology

Cell Signaling Technology (CST), the innovator in activation-state antibodies and related technologies, provides the highest quality reagents necessary to identify stem cells and elucidate signal transduction pathways involved in stem cell maintenance and differentiation. All CST antibodies are produced in-house and validated in applications including immunofluorescence, immunohistochemistry and flow cytometry. Moreover, technical support is provided by the same scientists who produce the product and know it best.


Celprogen  

Celprogen provides Stem Cell and Cell Biology products for Life Sciences, Pharmaceutical drug discovery and Diagnostics industries. Celprogen’s products are available as complete primary & established tissue culture system kits. Celprogen provides adult and embryonic Stem Cells with specific cell based assays for molecular diagnostics and therapeutics applications. Celprogen’s major organ system kits provide an excellent choice for drug discovery and pharmaceutical toxicology studies, for more product information visit www.celprogen.com.


Cognate Bioservices 

Cognate BioServices, Inc. was formed to provide full commercialization support to companies developing varied cellular technologies, encountering translational challenges in development, manufacturing, quality, regulatory and delivery. The expertise of the management team and staff provides a cost-effective solution to the need in the current market for early focus on product development and clinical phase planning, without the need for extensive capital outlay.



Miltenyi Biotec

Miltenyi Biotec provides products and services for pursuing life science research. Based on MACS® Technology, the portfolio includes over 600 products for the separation, cultivation, flow cytometric and molecular analysis of cells. The MACSmolecular business unit offers innovative solutions for molecular biology research, comprehensive microarray service, and microarray hybridization instrumentation.


Sigma-Aldrich

Sigma-Aldrich supplies the most complete line of high-quality, high-performance cell culture products in the industry. We offer a broad selection of media, sera, reagents, and analytical kits that span the needs of basic research applications as well as cGMP-compliant large-scale biopharmaceutical production. Included in these products is our new and expanding line of StemlineTM media products, designed for adult stem cell applications.


Stem Cell Innovations

SCI is a cell biology company with facilities in Scotch Plains, N.J., Houston, TX and in Leiden, the Netherlands. Stem Cell Innovations proprietary, human pluripotent stem cells, known as PluriCells, have the potential to aid in drug discovery, toxicology, and cell therapy. Stem Cell Innovations is in the process of making its patented pluripotent cell lines, which are eligible for federal funding in the U.S., widely available to universities and other not-for-profit institutions to rapidly advance stem cell research. Stem Cell Innovations is positioned to become a leading provider of toxicology testing and discovery systems for the pharmaceutical, chemical, and nutraceutical industries around the world. The development of the proprietary PluriCell technology greatly expands the Company’s currently marketed C3A human liver cell-based toxicology offerings. Additional information is available at www.stemcellinnovations.com.

 

 

 
Life Legal Defense Foundation supports ethical stem cell research, such as stem cell research using adult and umbilical cord stem cells, which have already produced many cures and therapies.

Quotations:

"...it is ridiculous for people who have already decided that it is moral to kill babies in the womb to show some squeamishness about destroying human embryos in a petri dish. Hell, man, once you decide to become a child-killer, their ages no longer matter. Or the numbers. Damnation of your soul is completed with the first one." Charley Reese 1
"...research involving human pluripotent stem cells...promises new treatments and possible cures for many debilitating diseases and injuries, including Parkinson's disease, diabetes, heart disease, multiple sclerosis, burns and spinal cord injuries. The NIH believes the potential medical benefits of human pluripotent stem cell technology are compelling and worthy of pursuit in accordance with appropriate ethical standards."  National Institutes of Health news release. 2
"Cal Thomas' article against stem cell research....is not particularly useful, because it does not deal with his fundamental belief that human personhood begins at conception. Similarly, articles by medical groups that promote stem cell research are not helpful, because they do not touch on their fundamental belief that embryos are not human persons. If there is to be any hope of resolving these issues, we must debate when human personhood begins. If we can reach a near consensus on this, then abortion, in-vitro fertilization, stem cell research and other debates will neatly resolve themselves." Comment letter to the Jewish World Review
The web site of CovenantNews.com on 2001-AUG-28 featured articles about stem cell research. Headings were:: "Murder by Abortion," "Get Your Human Sacrifice Grant Here," The file name is "murder.htm."


Google

 
Research in the human stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s

 

Stem cell treatments Medical researchers believe that stem cell therapy has the potential to radically change the treatment of human disease.

A number of adult stem cell therapies already exist, particularly bone marrow transplants that are used to treat leukaemia.

In the future, medical researchers anticipate being able to use technologies derived from stem cell research to treat a wider variety of diseases including cancer, parkinson's disease, spinal cord injuries, and muscle damage, amongst a number of other impairments and conditions.

However, there still exists a great deal of social and scientific uncertainty surrounding stem cell research, which could possibly be overcome through public debate and future research.

Stem cells, however, are already used extensively in research, and some scientists do not see cell therapy as the first goal of the research, but see the investigation of stem cells as a goal worthy in itself.

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