Some Definitions

eth-i-cal: (adj.) 1. Relating to morals, especially as concerning human conduct. 2. Morally correct.

le-gal: (adj.) 1. Of or based on law. 2. Appointed or required by law. 3. Permitted by law.

so-cial: (adj.) 1. Of or relating to society and its organization. 2. Concerned with the mutual relations of human beings. 3. Living in organized communities.

pol-i-cy: (n.) 1. Course or principle of action adopted or proposed by a government, party, business or individual, etc.

Definitions adapted from the Oxford Desk Dictionary and Thesaurus.

 

Stem Cell Research: Beyond Hype, Real Hope

The three broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, adult stem cells, which are found in adult tissues, and cord blood stem cells, which are found in the umbilical cord.

In a developing embryo, stem cells are able to differentiate into all of the specialized embryonic tissues.

In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialized cells.

As stem cells can be readily grown and transformed into specialised cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed.

In particular, embryonic cell lines, autologous embryonic stem cells generated through therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates.

Adult stem cells are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues.

Also known as somatic stem cells, they can be found in children, as well as adults. A great deal of adult stem cell research has focused on clarifying their capacity to divide or self-renew indefinitely and their differentiation potential.



NIH Human Embryonic Stem Cell Registry

The NIH Human Embryonic Stem Cell Registry lists the derivations of stem cells that are eligible for federal funding. The purpose of the Registry is to provide investigators with:

  • a unique NIH Code for each cell line that must be used when applying for NIH funding and
  • contact information to facilitate investigators' acquisition of stem cells.

Providers listed on this page have at least one line currently available for shipping; a second page lists providers of lines that are not currently available for distribution.

Both pages will be updated as more cell lines are made available by providers. Pages suitable for printing are available for:

(PDF files; get Adobe Reader)


Providers with Lines Available for Shipping
BresaGen, Inc.

Cell Lines

NIH Code: BG01, BG02, BG03, BG04*

Provider's Code: hESBGN-01, hESBGN-02, hESBGN-03, hESBGN-04*

Number Shipped: 75

* The cells failed to expand into undifferentiated cell cultures.

BresaGen may have sublines available for shipping. Contact BresaGen for more information about sublines. Subline BG01V is available for shipping. Contact ATCC for more information about BG01V.

Table of Cell Characteristics

Contact Information

Allan Robins, Ph.D.
Senior Vice President and Chief Scientific Officer
BresaGen, Inc.
111 Riverbend Road
Athens, GA 30605
Phone: 706-613-9878 x.158
Fax: 706-613-9879
E-mail: arobins@novocell.com

Memorandum of Understanding (27k PDF file; get Adobe Reader)
BresaGen 2004 hESC Methods Manual, v2.1 (600k PDF file; get Adobe Reader)

Cellartis AB

Cell Lines

NIH Code: SA01, SA02, SA03*

Provider's Code: Sahlgrenska 1, Sahlgrenska 2, Sahlgrenska 3*

Number Shipped: 13

* Cell line withdrawn by donor.

Cellartis may have sublines available for shipping. Contact Cellartis for more information about sublines.

Table of Cell Characteristics

Contact Information

Mikael Englund, Ph.D.
Phone: +46 (0)31 758 0921
E-mail: mikael.englund@cellartis.com

Johan Hyllner, Ph.D.
Phone: +46 (0)31 758 0902
E-mail: johan.hyllner@cellartis.com

Cellartis AB
Arvid Wallgrens Backe 20
SE-413 46 Göteborg
Sweden
Fax: +46 (0)31 758 0910
Web site: http://www.cellartis.com

Memorandum of Understanding (59k PDF file; get Adobe Reader)

ES Cell International

Cell Lines

NIH Code: ES01, ES02, ES03, ES04, ES05, ES06

Provider's Code: HES-1, HES-2, HES-3, HES-4, HES-5, HES-6

Number Shipped: 164

ESI lines are available at reduced cost through the National Stem Cell Bank.

ESI may have sublines available for shipping. Contact ESI for more information about sublines.

Table of Cell Characteristics

Contact Information

Suresh Chandran, IP and Licensing Manager
ES Cell International Pte Ltd
11 Biopolis Way
# 05-06 Helios
Singapore 138667
Phone: +65-6774-9570
Fax: +65-6774-5077
E-mail: schandran@escellinternational.com
Web site: http://www.escellinternational.com

Simple Letter of Agreement (30k PDF file; get Adobe Reader)

National Stem Cell Bank

Cell Lines

Number Shipped: 289

The National Stem Cell Bank (NSCB) distributes eligible human embryonic stem cell lines at reduced cost.

Contact the National Stem Cell Bank for more information.

Contact Information

WiCell Research Institute
P.O. Box 7365
Madison, WI 53707-7365
Phone: 608-263-6297
Fax: 608-263-1064
E-mail: info@wicell.org
Web site: http://www.nationalstemcellbank.org

Technion-Israel Institute of Technology

Cell Lines

NIH Code: TE03, TE32*, TE33*, TE04, TE06, TE62*, TE07*, TE72*

Provider's Code: I 3, I 3.2*, I 3.3*, I 4, I 6, I 6.2*, J 3*, J 3.2*

Number Shipped: 95

Technion may have sublines available for shipping. Contact Technion for more information about sublines.

* These lines are not yet available for shipping.

Table of Cell Characteristics

Contact Information

Dr. Joseph Itskovitz, M.D., D.Sc.
Rambam Medical Center
Department of OB/GYN
POB 9602
Haifa 31096
Israel
Phone: 972-4-8542536
Fax: 972-4-8542503
E-mail: itskovitz@rambam.health.gov.il
Web site: http://www.technion.ac.il

Material Transfer Agreement (80K PDF file; get Adobe Reader)

University of California, San Francisco

Cell Lines

NIH Code: UC01, UC06

Provider's Code: HSF-1, HSF-6

Number Shipped: 133

UCSF lines are available at reduced cost through the National Stem Cell Bank.

UCSF may have sublines available for shipping. Contact UCSF for more information about sublines.

Table of Cell Characteristics

Contact Information

Dr. Renee Reijo Pera, Ph.D.
Department of Obstetrics, Gynecology & Reproductive Sciences
Box 0556, Core Campus, HSE 1636
University of California, San Francisco
San Francisco, CA 94143-0556
Phone: 415-476-3178
Fax: 415-476-3121
E-mail: reijo@itsa.ucsf.edu
Web site: http://escells.ucsf.edu

Memorandum of Understanding (40k PDF file; get Adobe Reader)
Material Transfer Agreement

Wisconsin Alumni Research Foundation (WARF) (WiCell Research Institute)

Cell Lines

NIH Code: WA01, WA07, WA09, WA13, WA14

Provider's Code: H1, H7, H9, H13, H14

Number Shipped: 321

WiCell lines are available at reduced cost through the National Stem Cell Bank.

WiCell also may have sublines available for shipping. Contact WiCell for more information.

Table of Cell Characteristics

Contact Information

Tammy Torbleau
Secretary, Licensing Department
Wisconsin Alumni Research Foundation
P.O. Box 7365
Madison, WI 53707-7365
Phone: 608-263-6297
Fax: 608-263-1064
E-mail: info@wicell.org
Web site: http://www.warf.org
Web site: http://www.wicell.org

Memorandum of Understanding (22k PDF file; get Adobe Reader)
Technical Information: Protocols & Work Flow
FAQs About WiCell's Policies on the Use of Its hESC Lines (136k PDF file; get Adobe Reader)

 

 

 

Life Legal Defense Foundation supports ethical stem cell research, such as stem cell research using adult and umbilical cord stem cells, which have already produced many cures and therapies.

Quotations:

"...it is ridiculous for people who have already decided that it is moral to kill babies in the womb to show some squeamishness about destroying human embryos in a petri dish. Hell, man, once you decide to become a child-killer, their ages no longer matter. Or the numbers. Damnation of your soul is completed with the first one." Charley Reese 1
"...research involving human pluripotent stem cells...promises new treatments and possible cures for many debilitating diseases and injuries, including Parkinson's disease, diabetes, heart disease, multiple sclerosis, burns and spinal cord injuries. The NIH believes the potential medical benefits of human pluripotent stem cell technology are compelling and worthy of pursuit in accordance with appropriate ethical standards."  National Institutes of Health news release. 2
"Cal Thomas' article against stem cell research....is not particularly useful, because it does not deal with his fundamental belief that human personhood begins at conception. Similarly, articles by medical groups that promote stem cell research are not helpful, because they do not touch on their fundamental belief that embryos are not human persons. If there is to be any hope of resolving these issues, we must debate when human personhood begins. If we can reach a near consensus on this, then abortion, in-vitro fertilization, stem cell research and other debates will neatly resolve themselves." Comment letter to the Jewish World Review
The web site of CovenantNews.com on 2001-AUG-28 featured articles about stem cell research. Headings were:: "Murder by Abortion," "Get Your Human Sacrifice Grant Here," The file name is "murder.htm."


Google

 

Research in the human stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s

 

Stem cell treatments Medical researchers believe that stem cell therapy has the potential to radically change the treatment of human disease.

A number of adult stem cell therapies already exist, particularly bone marrow transplants that are used to treat leukaemia.

In the future, medical researchers anticipate being able to use technologies derived from stem cell research to treat a wider variety of diseases including cancer, parkinson's disease, spinal cord injuries, and muscle damage, amongst a number of other impairments and conditions.

However, there still exists a great deal of social and scientific uncertainty surrounding stem cell research, which could possibly be overcome through public debate and future research.

Stem cells, however, are already used extensively in research, and some scientists do not see cell therapy as the first goal of the research, but see the investigation of stem cells as a goal worthy in itself.

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